Impact of the COVID-19 Pandemic on Health-related Quality of Life in Children with Early Onset Scoliosis Original Research

Main Article Content

Jennifer A. Kunes
Divya Raman
Hiroko Matsumoto
Afrain Boby
Sumeet Garg
Joshua Pahys
Benjamin Roye
Michael G. Vitale
Pediatric Spine Study Group


Background: Throughout the COVID-19 pandemic, decreases in health-related quality of life (HRQoL) have been observed in adults and children, with isolation, economic disruption, school closures, and health-related anxiety likely contributing. In this study, we evaluated the impact of COVID-19 on self-reported HRQoL of EOS patients and their caregivers using the Early Onset Scoliosis Questionnaire-24 (EOSQ-24).

Methods: Patients with EOS and their caregivers enrolled in the Pediatric Spine Study Group (PSSG) registry with EOSQ scores from the year before the COVID-19 pandemic and the first year during COVID-19 were included. Two years of before-COVID-19 baseline EOSQ scores were recorded for each patient. We recorded patient medical demographics, scoliosis etiology, and comorbidities.

Results: 618 patients met inclusion criteria (255 male, 363 female). All EOSQ subscores increased significantly from pre-COVID to early-COVID (p < 0.001, p < 0.05, respectively), though the mean difference was well below the proposed EOSQ-24 MCID. There was no evidence of change in Combined HRQoL or impact- and satisfaction-related scores between early COVID to late COVID (p > 0.37). When stratified by etiology, there was no evidence of decrease in the HRQoL combined score or other subscores in any subgroup between pre-COVID and during COVID.

Conclusions: Overall, there was no evidence of negative impact on HRQoL by the COVID-19 pandemic for children with EOS or their caregivers. In the future, protective factors contributing to the resilience of this population may be explored further.

Article Details

How to Cite
Kunes, J. A., Raman, D., Matsumoto, H., Boby, A., Garg, S., Pahys, J., Roye, B., Vitale, M. G., & Study Group, P. S. (2022). Impact of the COVID-19 Pandemic on Health-related Quality of Life in Children with Early Onset Scoliosis: Original Research. Journal of the Pediatric Orthopaedic Society of North America, 4(4).